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|Job Category :
||Scientist/Senior Scientist, Protein Engineering
||New York, NY 10014
|Job Description :
||Position – Scientist/Senior Scientist, Protein Engineering
Through single-cell biology, computational biology, and artificial intelligence, Immunai is reprogramming the immune system to develop improved drugs and therapeutics.
Immunai was founded in December 2018. We are a multidisciplinary team of immunologists, genomics technologists, computer scientists, engineers, mathematicians and operators singularly focused on solving an audacious challenge. Backed by some of the leading scientific minds in immunology, oncology, and single cell genomics, we are up for the challenge.
Immunai has begun the process of mapping millions of immune cells and their functions in order to build a proprietary data set for clinical immunological data. The immune system mapping will play an important role in boosting R&D efforts in developing targeted therapies for different diseases. The company noted that the immune system consists of trillions of cells that are divided into different cell types that perform different functions. Because of the complexity of the system, it can be difficult to determine how drugs will interact with the immune cells. This increased understanding can be used to boost clinical response to different cellular therapies.
Immunai’s mission is to map the immune system with neural networks and transfer learning techniques informed by deep immunology knowledge. We developed the tools and knowhow to help every immuno-oncology and cell therapy researcher excel at their job. This helps increase the speed in which drugs are developed and brought to market by elucidating their mechanisms of action and resistance.
For details – www.immunai.com , email@example.com
Responsible for developing and running in vitro potency assays, mAb binding and neutralization assay
Responsible for generation of Fab and Fab’2 from mAb preparation and purification
Responsible for the generation of plasmid constructs and the generation and maintenance of tool reagents such as reporter cell lines
Responsible for generation of cell lines and recombinant proteins by transient and stable transfection or lentivirus transduction
Interface with disease biology teams to coordinate evaluation of candidate therapeutics in in vitro studies
Coordinate with in vivo pharmacology team to evaluate PK/PD of candidate therapeutics
Develop robust data packages, co-author accompanying reports to support regulatory filing
Ph.D. in Biology, Molecular Biology, Biochemistry or related field with 0 – 3+ years of post-graduate experience or M.S. Biology, Molecular Biology, Biochemistry or related field with minimum of 2 years of post-graduate experience or B.S in Biology, Molecular Biology, Biochemistry or related field with a minimum of 5 years of post-graduate experience.
3 or more years of experience at high-growth biotechnology or pharmaceutical companies
Experience monoclonal antibody sequence optimization to de-risk clinical development
Familiar with methods to generate reporter cell lines
Experienced in the design of plasmid constructs to generate stable reporter cell lines
Familiarity with methods and work flow for the generation of novel monoclonal antibodies
Adept in ambiguous situations, flexible and comfortable making decisions using minimal available data
A proven ability to work cross-functionally and adapt to changing priorities while managing multiple commitments with accuracy and efficiency to meet deadlines
Strong organizational skills, attention to detail, ability to prioritize and meet deadlines in a fast-paced and multi-cultural environment
Desired Personal traits
You want to make an impact on humankind
You prioritize “We” over “I”
You enjoy getting things done – with super high quality
You collaborate effectively with people of diverse backgrounds and cultures
You have superior skills and experience, and constantly strive to be world-class in what you do
You constantly challenge your own assumptions, pushing for continuous improvement
You have a growth mindset
You make decisions that favor the company, not yourself or your team
You are candid, authentic, and transparent
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